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Showing posts from June, 2024

A CALL TO CREATIVITY

Hello and welcome to The Looking Glass, WBGS' very own Academic Blog.  This year we are planning to breathe new life into this amazing blog as the Academic Head Boy team for 2025- 2026! However, at the Looking Glass we need your help to catapult this blog into it's GOLDEN AGE.  We need your articles, your essays, your opinions and your finest work to MAKE THE LOOKING GLASS GREAT AGAIN! If you have read something interesting or watched something that sparked a thought on social media -  WRITE ABOUT IT! If you entered a competition, however big or small - WRITE ABOUT IT! If you are interested in a specific field, issue or period - WRITE ABOUT IT! If you have produced artwork, a piece of music or creative writing - WE WILL PUBLISH IT! Your creative skills have been called to action - now we must muster to create, discover and explore.  You are the creative minds of the future. The Plato's, the Newtons, the Angelo's, the Nietzsche's. This is your calling.  This is Y...

An insight into Neuroferritinopathy

by Rhys Doshi L6C  Neuroferritinopathy is a severe neurological disorder, which is triggered when there is a gradual accumulation of iron in the brain [1] . Neurodegeneration with brain iron accumulation (NBIA) refers to a group of rare diseases that share clinical characteristics associated with excessive iron accumulation in the basal ganglia as well as progressive neurological deficits, such as chorea, dystonia, parkinsonism and cognitive impairment. Neuroferritinopathy is a form of NBIA caused by mutations in the ferritin light chain (FTL1) gene on chromosome 19q13.3.The build-up of iron can be caused by several factors, including increased blood-brain barrier permeability, inflammation, redistribution of iron within the brain and changes in iron homoeostasis [2] .  The most common initial clinical manifestations of Neuroferritinopathy are chorea and dystonia, and only six patients have been described who initially presented with tremors [3] . A 27-year-old woman visited a...